HDL Cholesterol

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Measures HDL-D Cholesterol. Coral Clinical Systems has answered these concerns of the busy laboratory professional by engineering the “Flexipour”reagent system which comprises of individual liquid stable components, which when mixed together in recommended ratios generate a dependable liquid stable working reagent. Depending on the usage, individual reagents may be poured at one go or flexibly in smaller volumes. HDL particles serve to transport lipoprotenis in the blood-stream. HDL is know as”good cholesterol” because high levels are thought to lower the risk of heart disease and coronary artery disease. Low HDL cholestrol levels, are considerde a greater heart disease risk. Clinical diagnosis should not be made on a single test result but should intergrate clinical and other laboratory data. Direct determination of serum HDLc (high-density lipoprotein cholesterol) levels without the need for any pretreatment or centrifugation of the sample. the method depends on the properties of a detergent which solubilizes only the HDL so that the HDLc is released to react with the cholesterol esterase, cholesterol oxidase and chromogens to give color. The non HDL lipoproteins LDL, VLDL and chylomicrons are inhibited from reacting with the enzymes dud to absorption of the detergents on their surfaces. The intensity of the color formed is proportional to the HDLc concentration in the sample