For more information see this pdf file —-LDH-1 (rt click open in new tab)
Measures LDH Concentration. Coral Clinical Systems has answered these concerns of the busy laboratory professional by engineering the “Flexipour” reagent system which comprises of individual liquid stable components, which when mixed together in recommended ratios generate a dependable liquid stable working reagent. Depending on the usage, individual reagents may be poured at one go or flexibly in smaller volumes. LDH is found in many body tissues particularly heart, liver, skeletal muscle, kidney and RBC’s. LDH is found in the form of isoenzymes based on their electrophoretic mobility with each isoenzyme being primarily from different organs. Increased levels are found in myocardial infarction, pulmonary diseases, hepatic diseases, hemolytic anemias, renal diseases and muscular dystrophy. Lactate dehydrogenase catalyzes the reduction of pyruvate with NADH to form NAD. The rate of oxidation of NADH to NAD is measured as a decrease in absorbance which is proportional to the LDH activity in the sample.