for more information see these pdf files—- Uric Acid-1 Uric Acid-2 (rt click open in new tab)
Measures Uric Acid. Coral Clinical Systems has answered these concerns of the busy laboratory professional by engineering the “Flexipour” reagent system which comprises of individual liquid stable components, which when mixed together in recommended ratios generate a dependable liquid stable working reagent. Depending on the usage, individual reagents may be poured at one go or flexibly in smaller volumes. Uric acid is the end product of purine metabolism. Uric acid is excreted to a large degree by the kidneys and to a smaller degree in the intestinal tract by microbial degradation. Increased levels are found in Gout, arthritis, impaired renal functions. And starvation. Decreased levels are found in Wilson’s disease, Fanconi’s syndrome and yellow atrophy of the liver. Uricase converts uric acid to allantoin and hydrogen peroxide. The hydrogen peroxide formed further reacts with a phenolic compound and 4 amino antipyrine by the catalytic action of peroxidase to form a red coloured quinonimine dye complex. Intensity of the colour formed is directly proportional to the amount of uric acid present in the sample.